99 research outputs found
Knock-in of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like PhenoTypes
Footnotes We thank Roemex and the College for Life Science and Medicine at the University of Aberdeen for their generous support. The authors declare no competing financial interests.Peer reviewedPublisher PD
Between and within laboratory reliability of mouse behaviour recorded in home-cage and open-field
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The interoceptive hippocampus: mouse brain endocrine receptor expression highlights a dentate gyrus (DG)–cornu ammonis (CA) challenge–sufficiency axis
Funding: The authors received no specific funding for this work.Peer reviewedPublisher PD
Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
Date of Acceptance: 28/07/2015 The authors are grateful to the staff of the Medical Research Facility for their help with the animal care. This work was supported by the NHS Endowment fund 09/03 and the Wellcome Trust (WT080782MF). We thank Merck & Co. Inc., Rathway NJ, USA for the supply of DFU.Peer reviewedPublisher PD
Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology
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Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones
This work was funded by The BBSRC (BB/D004659/1) the Wellcome Trust (080980/Z/06/Z) and the Medical Research Council (G0701003). Colin Hay was funded by the Chief Scientist Office, Scotland. Scott Davidson was funded by a BBSRC strategic studentship (BBS/S/2005/12001). Philip Cowie was funded by the Scottish Universities Life Sciences Alliance (SULCA).Peer reviewedPublisher PD
Cerebellar molecular layer interneurons are dispensable for cued and contextual fear conditioning
Funding Information: We were supported by the Biotechnology and Biological Sciences Research Council grant BB/H001123/1 (P.W.), the Medical Research Council grants G1100546/2 and G0800399 (P.W.) and the University of Aberdeen (K.L.H.M.-P., M.W.-F., G.R. and P.W.). M.W.F. is currently supported by the Intramural Research Programme at the National Institute of Health, USA. Open Access funding enabled and organized by Projekt DEAL.Peer reviewedPublisher PD
Cannabinoids and their therapeutic applications in mental disorders
Open Access via PubMed Acknowledgments/Disclosures: This work was supported in part by funds from the Department of Biomedical Sciences Project (RICDIP_2012_Fratta_01), University of Cagliari. The authors declare no conflict of interest.Peer reviewedPublisher PD
Of mice and motion : Behavioural-EEG phenotyping of Alzheimer’s disease mouse models
This work was supported by the Alzheimer’s Society [project grant number AS-PG-14-039] to BP and GR.Peer reviewedPostprin
Comparison of automated video tracking systems in the open field test : ANY-Maze versus EthoVision XT
This project included funding from the Innovative Medicines Initiative 2/EFPIA, European Quality in Preclinical Data (EQIPD) consortium under grant agreement number 777364. We would also like to acknowledge the staff of the Medical Research Facility for their support with animal care, handling and behavioural experiments.Peer reviewedPostprin
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